000087654 001__ 87654
000087654 005__ 20220405150414.0
000087654 0247_ $$2doi$$a10.1016/j.trecan.2019.12.007
000087654 0248_ $$2sideral$$a115389
000087654 037__ $$aART-2020-115389
000087654 041__ $$aeng
000087654 100__ $$aRamírez-Labrada, Ariel G.
000087654 245__ $$aThe influence of lung microbiota on lung carcinogenesis, immunity and immunotherapy
000087654 260__ $$c2020
000087654 5060_ $$aAccess copy available to the general public$$fUnrestricted
000087654 5203_ $$aMicrobiota have emerged as key modulators of both the carcinogenic process and the immune response against cancer cells, and, thus, it seems to influence the efficacy of immunotherapy. While most studies have focused on analyzing the influence of gut microbiota, its composition substantially differs from that in the lung. Here, we describe how microbial life in the lungs is associated with host immune status in the lungs and, thus, how the identification of the microbial populations in the lower respiratory tract rather than in the gut might be key to understanding the lung carcinogenic process and to predict the efficacy of different treatments. Understanding the influence of lung microbiota on host immunity may identify new therapeutic targets and help to design new immunotherapy approaches to treat lung cancer.
000087654 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000087654 590__ $$a14.226$$b2020
000087654 591__ $$aONCOLOGY$$b14 / 242 = 0.058$$c2020$$dQ1$$eT1
000087654 592__ $$a4.174$$b2020
000087654 593__ $$aOncology$$c2020$$dQ1
000087654 593__ $$aCancer Research$$c2020$$dQ1
000087654 655_4 $$ainfo:eu-repo/semantics/review$$vinfo:eu-repo/semantics/publishedVersion
000087654 700__ $$aIsla, Dolores
000087654 700__ $$aArtal, Angel
000087654 700__ $$aArias, Maykel
000087654 700__ $$0(orcid)0000-0001-7294-245X$$aRezusta, Antonio$$uUniversidad de Zaragoza
000087654 700__ $$0(orcid)0000-0003-0154-0730$$aPardo, Julián$$uUniversidad de Zaragoza
000087654 700__ $$aGálvez, Eva M.
000087654 7102_ $$11011$$2630$$aUniversidad de Zaragoza$$bDpto. Microb.Ped.Radio.Sal.Pú.$$cÁrea Microbiología
000087654 7102_ $$11011$$2566$$aUniversidad de Zaragoza$$bDpto. Microb.Ped.Radio.Sal.Pú.$$cÁrea Inmunología
000087654 773__ $$g6, 2 (2020), P86-97$$pTrends cancer$$tTrends in Cancer$$x2405-8033
000087654 8564_ $$s1569785$$uhttps://zaguan.unizar.es/record/87654/files/texto_completo.pdf$$yVersión publicada
000087654 8564_ $$s109183$$uhttps://zaguan.unizar.es/record/87654/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000087654 909CO $$ooai:zaguan.unizar.es:87654$$particulos$$pdriver
000087654 951__ $$a2022-04-05-14:36:02
000087654 980__ $$aARTICLE