000070673 001__ 70673
000070673 005__ 20220831095642.0
000070673 0247_ $$2doi$$a10.1155/2016/8503859
000070673 0248_ $$2sideral$$a106042
000070673 037__ $$aART-2016-106042
000070673 041__ $$aeng
000070673 100__ $$0(orcid)0000-0002-1609-5994$$aSatue, M.
000070673 245__ $$aOptical Coherence Tomography as a Biomarker for Diagnosis, Progression, and Prognosis of Neurodegenerative Diseases
000070673 260__ $$c2016
000070673 5060_ $$aAccess copy available to the general public$$fUnrestricted
000070673 5203_ $$aNeurodegenerative diseases present a current challenge for accurate diagnosis and for providing precise prognostic information. Developing imaging biomarkers for multiple sclerosis (MS), Parkinson disease (PD), and Alzheimer’s disease (AD) will improve the clinical management of these patients and may be useful for monitoring treatment effectiveness. Recent research using optical coherence tomography (OCT) has demonstrated that parameters provided by this technology may be used as potential biomarkers for MS, PD, and AD. Retinal thinning has been observed in these patients and new segmentation software for the analysis of the different retinal layers may provide accurate information on disease progression and prognosis. In this review we analyze the application of retinal evaluation using OCT technology to provide better understanding of the possible role of the retinal layers thickness as biomarker for the detection of these neurodegenerative pathologies. Current OCT analysis of the retinal nerve fiber layer and, specially, the ganglion cell layer thickness may be considered as a good biomarker for disease diagnosis, severity, and progression.
000070673 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000070673 590__ $$a1.712$$b2016
000070673 591__ $$aOPHTHALMOLOGY$$b35 / 59 = 0.593$$c2016$$dQ3$$eT2
000070673 591__ $$aMEDICINE, RESEARCH & EXPERIMENTAL$$b84 / 128 = 0.656$$c2016$$dQ3$$eT2
000070673 592__ $$a0.812$$b2016
000070673 593__ $$aOphthalmology$$c2016$$dQ2
000070673 655_4 $$ainfo:eu-repo/semantics/review$$vinfo:eu-repo/semantics/publishedVersion
000070673 700__ $$aObis, J.
000070673 700__ $$aRodrigo, M.J.
000070673 700__ $$0(orcid)0000-0002-6591-0801$$aOtin, S.$$uUniversidad de Zaragoza
000070673 700__ $$0(orcid)0000-0002-4316-1635$$aFuertes, M.I.$$uUniversidad de Zaragoza
000070673 700__ $$0(orcid)0000-0001-9411-5834$$aVilades, E.
000070673 700__ $$aGracia, H.
000070673 700__ $$0(orcid)0000-0002-9788-2083$$aAra, J.R.
000070673 700__ $$aAlarcia, R.
000070673 700__ $$0(orcid)0000-0002-1402-3129$$aPolo, V.$$uUniversidad de Zaragoza
000070673 700__ $$0(orcid)0000-0002-6745-7668$$aLarrosa, J.M.$$uUniversidad de Zaragoza
000070673 700__ $$0(orcid)0000-0003-2389-8282$$aPablo, L.E.$$uUniversidad de Zaragoza
000070673 700__ $$0(orcid)0000-0001-6258-2489$$aGarcia-Martin, E.$$uUniversidad de Zaragoza
000070673 7102_ $$11004$$2646$$aUniversidad de Zaragoza$$bDpto. Cirugía,Ginecol.Obstetr.$$cÁrea Oftalmología
000070673 7102_ $$12002$$2647$$aUniversidad de Zaragoza$$bDpto. Física Aplicada$$cÁrea Óptica
000070673 773__ $$g2016 (2016), 8503859 [9 pp.]$$pJ. Ophthalmol.$$tJournal of Ophthalmology$$x2090-004X
000070673 8564_ $$s3160309$$uhttps://zaguan.unizar.es/record/70673/files/texto_completo.pdf$$yVersión publicada
000070673 8564_ $$s103919$$uhttps://zaguan.unizar.es/record/70673/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000070673 909CO $$ooai:zaguan.unizar.es:70673$$particulos$$pdriver
000070673 951__ $$a2022-08-31-09:48:13
000070673 980__ $$aARTICLE