000070349 001__ 70349
000070349 005__ 20191122145054.0
000070349 0247_ $$2doi$$a10.1515/jpm-2016-0298
000070349 0248_ $$2sideral$$a98716
000070349 037__ $$aART-2018-98716
000070349 041__ $$aeng
000070349 100__ $$0(orcid)0000-0001-9585-0187$$aSavirón Cornudella, Ricardo$$uUniversidad de Zaragoza
000070349 245__ $$aComparison of fetal weight distribution improved by paternal height by Spanish standard versus Intergrowth 21st standard
000070349 260__ $$c2018
000070349 5060_ $$aAccess copy available to the general public$$fUnrestricted
000070349 5203_ $$aOBJECTIVE: Our main objective was to study the influence on birth and ultrasound fetal weight of traditional factors in combination with non-traditionally explored predictors such as paternal height to provide a new customized in utero growth model. We also have compared it in our population with other customized and non-customized models.
METHODS: We collected 5243 cases of singleton pregnancies. An integrated study of the different variables was performed in a multivariate model to predict the fetus birthweight and customized growth curves were created following the Gardosi procedure.
RESULTS: Gestational age (P<0.001), parity (P<0.001), maternal age (P<0.001), maternal body mass index (P<0.001), maternal height (P<0.001), parental height (P<0.001), pregnancy-associated plasma protein A (PAPP-A) (P<0.001), free-beta human chorionic gonadotropin (FBHCG) (P<0.013), single umbilical artery (SUA) (P<0.009), region of origin (P<0.001), fetal sex (P<0.001), smoking (P<0.001) and pre-gestational diabetes (P<0.001) showed statistical significance. We created two growth customized models (simple and advance) that have shown good performance in predicting fetal weight at delivery and estimated by ultrasounds. The percentage of small for gestational age (SGA) cases (P10) predicted by the two models at birth were 9.9% and 9%, and for large gestational ages (LGA) (P90) we obtained values of 90.1% and 90.3%. Also, using the fetal weights measured by ultrasounds, we obtained P10 adjusted predictions, 9.2% and 9.4%, for the simpler and advance models, respectively, which were more adjusted than the 0.4, 4.6 and 10.6 obtained using the other compared models. For an easy use of models an app and a nomogram is provided.
CONCLUSION: Using new predictor variables we implemented new growth in utero model, with predictions more adjusted to our population than Spanish customized or Intergrowth 21st models with better performance for birth and ultrasound fetal weights. We propose using a prediction model that includes parental height.
000070349 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000070349 590__ $$a1.361$$b2018
000070349 591__ $$aPEDIATRICS$$b80 / 124 = 0.645$$c2018$$dQ3$$eT2
000070349 591__ $$aOBSTETRICS & GYNECOLOGY$$b65 / 83 = 0.783$$c2018$$dQ4$$eT3
000070349 592__ $$a0.522$$b2018
000070349 593__ $$aPediatrics, Perinatology and Child Health$$c2018$$dQ2
000070349 593__ $$aObstetrics and Gynecology$$c2018$$dQ2
000070349 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000070349 700__ $$0(orcid)0000-0002-3007-302X$$aEsteban Escaño, Luis Mariano
000070349 700__ $$0(orcid)0000-0003-0691-0251$$aLerma, Diego$$uUniversidad de Zaragoza
000070349 700__ $$aCotaina, Laura
000070349 700__ $$0(orcid)0000-0003-0178-4567$$aBorque Fernando, Ángel$$uUniversidad de Zaragoza
000070349 700__ $$0(orcid)0000-0002-6474-2252$$aSanz Sáiz, Gerardo$$uUniversidad de Zaragoza
000070349 700__ $$0(orcid)0000-0002-9048-121X$$aCastán, Sergio$$uUniversidad de Zaragoza
000070349 7102_ $$12007$$2265$$aUniversidad de Zaragoza$$bDpto. Métodos Estadísticos$$cÁrea Estadís. Investig. Opera.
000070349 7102_ $$11003$$2027$$aUniversidad de Zaragoza$$bDpto. Anatom.Histolog.Humanas$$cArea Anatom.Embriol.Humana
000070349 7102_ $$11004$$2645$$aUniversidad de Zaragoza$$bDpto. Cirugía,Ginecol.Obstetr.$$cÁrea Obstetricia y Ginecología
000070349 7102_ $$11004$$2817$$aUniversidad de Zaragoza$$bDpto. Cirugía,Ginecol.Obstetr.$$cÁrea Urología
000070349 773__ $$g46, 7 (2018), 750-759$$pJ. perinat. med.$$tJOURNAL OF PERINATAL MEDICINE$$x0300-5577
000070349 8564_ $$s1709799$$uhttps://zaguan.unizar.es/record/70349/files/texto_completo.pdf$$yVersión publicada
000070349 8564_ $$s121090$$uhttps://zaguan.unizar.es/record/70349/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000070349 909CO $$ooai:zaguan.unizar.es:70349$$particulos$$pdriver
000070349 951__ $$a2019-11-22-14:44:43
000070349 980__ $$aARTICLE