000070254 001__ 70254
000070254 005__ 20200117213749.0
000070254 0247_ $$2doi$$a10.3390/nu10020246
000070254 0248_ $$2sideral$$a105341
000070254 037__ $$aART-2018-105341
000070254 041__ $$aeng
000070254 100__ $$aBallesteros-Pomar, María D.
000070254 245__ $$aCost-effectiveness of a specialized oral nutritional supplementation for malnourished older adult patients in Spain
000070254 260__ $$c2018
000070254 5060_ $$aAccess copy available to the general public$$fUnrestricted
000070254 5203_ $$aMalnutrition has been related to prolonged hospital stays, and to increases in readmission and mortality rates. In the NOURISH (Nutrition effect On Unplanned Readmissions and Survival in Hospitalized patients) study, administering a high protein oral nutritional supplement (ONS) containing beta-hydroxy-beta-methylbutyrate (HP-HMB) to hospitalised older adult patients led to a significant improvement in survival compared with a placebo treatment. The aim of this study was to determine whether HP-HMB would be cost-effective in Spain. We performed a cost-effectiveness analysis from the perspective of the Spanish National Health System using time horizons of 90 days, 180 days, 1 year, 2 years, 5 years and lifetime. The difference in cost between patients treated with HP-HMB and placebo was €332.75. With the 90 days time horizon, the difference in life years gained (LYG) between both groups was 0.0096, resulting in an incremental cost-effectiveness ratio (ICER) of €34, 700.62/LYG.With time horizons of 180 days, 1 year, 2 years, 5 years and lifetime, the respective ICERs were €13, 711.68, €3377.96, €2253.32, €1127.34 and €563.84/LYG. This analysis suggests that administering HP-HMB to older adult patients admitted to Spanish hospitals during hospitalisation and after discharge could be a cost-effective intervention that would improve survival with a reduced marginal cost.
000070254 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000070254 590__ $$a4.171$$b2018
000070254 591__ $$aNUTRITION & DIETETICS$$b16 / 86 = 0.186$$c2018$$dQ1$$eT1
000070254 592__ $$a1.493$$b2018
000070254 593__ $$aNutrition and Dietetics$$c2018$$dQ1
000070254 593__ $$aFood Science$$c2018$$dQ1
000070254 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000070254 700__ $$aMartínez Llinàs, Diana
000070254 700__ $$aGoates, Scott
000070254 700__ $$aSanz Barriuso, Rebeca
000070254 700__ $$0(orcid)0000-0002-7758-3588$$aSanz-Paris, Alejandro$$uUniversidad de Zaragoza
000070254 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina
000070254 773__ $$g10, 2 (2018), 246 [11 pp]$$pNUTRIENTS$$tNutrients$$x2072-6643
000070254 85641 $$uhttps://www.mdpi.com/2072-6643/10/2/246/htm$$zTexto completo de la revista
000070254 8564_ $$s392968$$uhttps://zaguan.unizar.es/record/70254/files/texto_completo.pdf$$yVersión publicada
000070254 8564_ $$s118134$$uhttps://zaguan.unizar.es/record/70254/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000070254 909CO $$ooai:zaguan.unizar.es:70254$$particulos$$pdriver
000070254 951__ $$a2020-01-17-21:31:30
000070254 980__ $$aARTICLE