000064359 001__ 64359
000064359 005__ 20200221144344.0
000064359 0247_ $$2doi$$a10.1016/j.tjog.2015.12.022
000064359 0248_ $$2sideral$$a97405
000064359 037__ $$aART-2016-97405
000064359 041__ $$aeng
000064359 100__ $$aAdiego-Calvo, I.
000064359 245__ $$aAre congenital malformations more frequent in fetuses with intrahepatic persistent right umbilical vein? A comparative study
000064359 260__ $$c2016
000064359 5060_ $$aAccess copy available to the general public$$fUnrestricted
000064359 5203_ $$aObjective Persistent right umbilical vein (PRUV) is a vascular anomaly where the right umbilical vein remains as the only conduit that returns oxygenated blood to the fetus. It has classically been described as associated with numerous defects. We distinguish the intrahepatic variant (better prognosis) and the extrahepatic variant (associated with worse prognosis). The objective of this study was to compare rates of congenital malformations in fetuses with intrahepatic PRUV (I-PRUV) versus singleton pregnancies without risk factors. Materials and Methods A multicenter, crossover design, comparative study was performed between 2003 and 2013 on fetuses diagnosed with I-PRUV (n = 56), and singleton pregnancies without congenital malformation risk factors (n = 4050). Results Fifty-six cases of I-PRUV were diagnosed (incidence 1:770). A statistically significant association between I-PRUV and the presence of congenital malformations (odds ratio 4.321; 95% confidence interval 2.15–8.69) was found. This positive association was only observed with genitourinary malformations (odds ratio 3.038; 95% confidence interval 1.08–8.56). Conclusion Our rate of malformations associated with I-PRUV (17.9%) is similar to previously published rates. I-PRUV has shown a significant increase in the rate of associated malformations, although this association has only been found to be statistically significant in the genitourinary system. Noteworthy is the fact that this comparative study has not pointed to a significant increase in the congenital heart malformation rate. Diagnosis of isolated I-PRUV does not carry a worse prognosis.
000064359 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000064359 590__ $$a0.925$$b2016
000064359 591__ $$aOBSTETRICS & GYNECOLOGY$$b73 / 80 = 0.913$$c2016$$dQ4$$eT3
000064359 592__ $$a0.416$$b2016
000064359 593__ $$aObstetrics and Gynecology$$c2016$$dQ3
000064359 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000064359 700__ $$0(orcid)0000-0001-9585-0187$$aSaviron-Cornudella, R.
000064359 700__ $$aMartinez-Payo, C.
000064359 700__ $$0(orcid)0000-0002-9273-5885$$aRubio-Aranda, E.$$uUniversidad de Zaragoza
000064359 700__ $$aSancho-Sauco, J.
000064359 700__ $$0(orcid)0000-0002-5494-343X$$aCisneros-Gimeno, A.$$uUniversidad de Zaragoza
000064359 700__ $$0(orcid)0000-0003-1595-8345$$aPerez-Perez, P.$$uUniversidad de Zaragoza
000064359 700__ $$0(orcid)0000-0003-0691-0251$$aLerma-Puertas, D.$$uUniversidad de Zaragoza
000064359 700__ $$0(orcid)0000-0001-9372-4267$$aWhyte-Orozco, J.$$uUniversidad de Zaragoza
000064359 7102_ $$11003$$2027$$aUniversidad de Zaragoza$$bDpto. Anatom.Histolog.Humanas$$cArea Anatom.Embriol.Humana
000064359 7102_ $$11004$$2645$$aUniversidad de Zaragoza$$bDpto. Cirugía,Ginecol.Obstetr.$$cÁrea Obstetricia y Ginecología
000064359 7102_ $$11008$$2615$$aUniversidad de Zaragoza$$bDpto. Microb.Med.Pr.,Sal.Públ.$$cÁrea Medic.Prevent.Salud Públ.
000064359 773__ $$g55, 6 (2016), 782-785$$pTaiwan. j. obstet. gynecol.$$tTAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY$$x1028-4559
000064359 8564_ $$s498936$$uhttps://zaguan.unizar.es/record/64359/files/texto_completo.pdf$$yVersión publicada
000064359 8564_ $$s98977$$uhttps://zaguan.unizar.es/record/64359/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000064359 909CO $$ooai:zaguan.unizar.es:64359$$particulos$$pdriver
000064359 951__ $$a2020-02-21-13:51:47
000064359 980__ $$aARTICLE