000063420 001__ 63420
000063420 005__ 20190709135510.0
000063420 0247_ $$2doi$$a10.1016/j.tet.2016.08.074
000063420 0248_ $$2sideral$$a101613
000063420 037__ $$aART-2017-101613
000063420 041__ $$aeng
000063420 100__ $$aMartínez, Alejandro V.
000063420 245__ $$aAn expedient synthesis of resveratrol through a highly recoverable palladium catalyst
000063420 260__ $$c2017
000063420 5060_ $$aAccess copy available to the general public$$fUnrestricted
000063420 5203_ $$aA straightforward two-step synthesis of resveratrol is described, with total isolated yields in the range of 75–80%. The key synthetic step, a Heck–Mizoroki C[sbnd]C cross-coupling reaction, is efficiently promoted by a heterogeneous catalyst consisting of palladium nanoparticles supported on synthetic clay. This solid catalyst is quite handy and displays high stability and robustness under reaction conditions. The catalyst can be easily recovered and reused at least 10 times, which improves the overall catalytic efficiency of the system. Moreover, the use of solvents is limited, and the reaction procedure allows a facile separation and purification of the desired product, free from the concomitant ionic by-product and from palladium contamination.
000063420 536__ $$9info:eu-repo/grantAgreement/ES/DGA/E11$$9info:eu-repo/grantAgreement/ES/MINECO/CTQ2014-52367-R
000063420 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000063420 590__ $$a2.377$$b2017
000063420 591__ $$aCHEMISTRY, ORGANIC$$b23 / 57 = 0.404$$c2017$$dQ2$$eT2
000063420 592__ $$a0.8$$b2017
000063420 593__ $$aBiochemistry$$c2017$$dQ2
000063420 593__ $$aOrganic Chemistry$$c2017$$dQ2
000063420 593__ $$aDrug Discovery$$c2017$$dQ2
000063420 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000063420 700__ $$0(orcid)0000-0003-1199-2087$$aGarcía, José I.
000063420 700__ $$0(orcid)0000-0003-1570-4257$$aMayoral, José A.$$uUniversidad de Zaragoza
000063420 7102_ $$12013$$2765$$aUniversidad de Zaragoza$$bDpto. Química Orgánica$$cÁrea Química Orgánica
000063420 773__ $$g73, 38 (2017), 5581-5584$$pTetrahedron$$tTETRAHEDRON$$x0040-4020
000063420 8564_ $$s424709$$uhttps://zaguan.unizar.es/record/63420/files/texto_completo.pdf$$yPostprint
000063420 8564_ $$s93423$$uhttps://zaguan.unizar.es/record/63420/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000063420 909CO $$ooai:zaguan.unizar.es:63420$$particulos$$pdriver
000063420 951__ $$a2019-07-09-11:51:00
000063420 980__ $$aARTICLE