000063319 001__ 63319
000063319 005__ 20171129112117.0
000063319 0247_ $$2doi$$a10.1371/journal.pone.0106370
000063319 0248_ $$2sideral$$a98814
000063319 037__ $$aART-2014-98814
000063319 041__ $$aeng
000063319 100__ $$aMoreno-Peral, P.
000063319 245__ $$aPredicting the onset of anxiety syndromes at 12 months in primary care attendees. The predictA-Spain study
000063319 260__ $$c2014
000063319 5060_ $$aAccess copy available to the general public$$fUnrestricted
000063319 5203_ $$aBackground: There are no risk algorithms for the onset of anxiety syndromes at 12 months in primary care. We aimed to develop and validate internally a risk algorithm to predict the onset of anxiety syndromes at 12 months. Methods: A prospective cohort study with evaluations at baseline, 6 and 12 months. We measured 39 known risk factors and used multilevel logistic regression and inverse probability weighting to build the risk algorithm. Our main outcome was generalized anxiety, panic and other non-specific anxiety syndromes as measured by the Primary Care Evaluation of Mental Disorders, Patient Health Questionnaire (PRIME-MD-PHQ). We recruited 3, 564 adult primary care attendees without anxiety syndromes from 174 family physicians and 32 health centers in 6 Spanish provinces. Results: The cumulative 12-month incidence of anxiety syndromes was 12.2%. The predictA-Spain risk algorithm included the following predictors of anxiety syndromes: province; sex (female); younger age; taking medicines for anxiety, depression or stress; worse physical and mental quality of life (SF-12); dissatisfaction with paid and unpaid work; perception of financial strain; and the interactions sex*age, sex*perception of financial strain, and age*dissatisfaction with paid work. The C-index was 0.80 (95% confidence interval = 0.78-0.83) and the Hedges'' g = 1.17 (95% confidence interval = 1.04-1.29). The Copas shrinkage factor was 0.98 and calibration plots showed an accurate goodness of fit. Conclusions: The predictA-Spain risk algorithm is valid to predict anxiety syndromes at 12 months. Although external validation is required, the predictA-Spain is available for use as a predictive tool in the prevention of anxiety syndromes in primary care.
000063319 536__ $$9info:eu-repo/grantAgreement/ES/DGA/RD06-0018-0020-Aragon group$$9info:eu-repo/grantAgreement/ES/ISCIII/PI04-1771$$9info:eu-repo/grantAgreement/ES/ISCIII/PI04-1980$$9info:eu-repo/grantAgreement/ES/ISCIII/PI04-2450$$9info:eu-repo/grantAgreement/ES/ISCIII/PI06-1442
000063319 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000063319 590__ $$a3.234$$b2014
000063319 591__ $$aMULTIDISCIPLINARY SCIENCES$$b9 / 57 = 0.158$$c2014$$dQ1$$eT1
000063319 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000063319 700__ $$aDe Dios Luna, J.
000063319 700__ $$aMarston, L.
000063319 700__ $$aKing, M.
000063319 700__ $$aNazareth, I.
000063319 700__ $$aMotrico, E.
000063319 700__ $$aGildegómez-Barragán, M. J.
000063319 700__ $$aTorres-González, F.
000063319 700__ $$aMontón-Franco, C.$$uUniversidad de Zaragoza
000063319 700__ $$aSánchez-Celaya, M.
000063319 700__ $$aDíaz-Barreiros, M. A.
000063319 700__ $$aVicens, C.
000063319 700__ $$aMuñoz-Bravo, C.
000063319 700__ $$aBellón, J. Á.
000063319 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDepartamento de Medicina, Psiquiatría y Dermatología$$cMedicina
000063319 773__ $$g9, 9 (2014), e106370 [14 pp]$$pPLoS One$$tPLoS One$$x1932-6203
000063319 8564_ $$s355070$$uhttps://zaguan.unizar.es/record/63319/files/texto_completo.pdf$$yVersión publicada
000063319 8564_ $$s122184$$uhttps://zaguan.unizar.es/record/63319/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000063319 909CO $$ooai:zaguan.unizar.es:63319$$particulos$$pdriver
000063319 951__ $$a2017-11-28-13:51:16
000063319 980__ $$aARTICLE