000062039 001__ 62039
000062039 005__ 20171211140547.0
000062039 0247_ $$2doi$$a10.5424/sjar/2014123-5489
000062039 0248_ $$2sideral$$a87823
000062039 037__ $$aART-2014-87823
000062039 041__ $$aeng
000062039 100__ $$aSalazar, E.
000062039 245__ $$aLack of relationship between Visna/maedi infection and scrapie resistance genetic markers
000062039 260__ $$c2014
000062039 5060_ $$aAccess copy available to the general public$$fUnrestricted
000062039 5203_ $$aThe relationship between Visna/maedi virus (VMV) antibody status and scrapie genetic resistance of 10,611 Rasa Aragonesa sheep from 17 flocks in Aragón (Spain) was investigated. The fifteen most common PRNP gene haplotypes and genotypes were identified and the genotypes were classified into the corresponding scrapie risk groups (groups 1 to 5). ARQ (93.3%) and ARR (31.8%) were the most common haplotypes and ARQ/ARQ (56%) and ARR/ARQ (25.6%) were the most common genotypes. The frequencies of scrapie risk groups 1, 2, 3, 4 and 5 were 3.3%, 27.3%, 63.5%, 1.2% and 4.8%, respectively. Overall Visna/maedi seroprevalence was 53% and flock seroprevalence ranged between 21-86%. A random effects logistic regression model indicated that sheep VMV serological status (outcome variable) was not associated with any particular scrapie risk group. Instead, VMV seropositivity progressively increased with age, was signif icantly greater in females compared to males and varied between flocks. The absence of a relationship between VMV infection and scrapie genotypes is important for VMV control and specifically for sheep participating in an ELISA-based Visna/maedi control program.
000062039 536__ $$9info:eu-repo/grantAgreement/ES/MICINN/AGL2007-66874-C04-02 GAN$$9info:eu-repo/grantAgreement/ES/MINECO/AGL2010-22341-C04-02 GAN
000062039 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000062039 590__ $$a0.703$$b2014
000062039 591__ $$aAGRICULTURE, MULTIDISCIPLINARY$$b25 / 56 = 0.446$$c2014$$dQ2$$eT2
000062039 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000062039 700__ $$aBerriatua, E.
000062039 700__ $$aPérez, M.
000062039 700__ $$aMarín, B.
000062039 700__ $$0(orcid)0000-0001-5105-6133$$aAcín, C.$$uUniversidad de Zaragoza
000062039 700__ $$0(orcid)0000-0001-6016-4726$$aMartín-Burriel, I.$$uUniversidad de Zaragoza
000062039 700__ $$aReina, R.
000062039 700__ $$ade Andrés, D.
000062039 700__ $$aAmorena, B.
000062039 700__ $$0(orcid)0000-0002-7173-7216$$aBadiola, J. J.$$uUniversidad de Zaragoza
000062039 700__ $$0(orcid)0000-0002-2053-9842$$aLuján, L.$$uUniversidad de Zaragoza
000062039 7102_ $$11009$$2773$$aUniversidad de Zaragoza$$bDepartamento de Patología Animal$$cSanidad Animal
000062039 7102_ $$11001$$2420$$aUniversidad de Zaragoza$$bDepartamento de Anatomía, Embriología y Genética Animal$$cGenética
000062039 773__ $$g12, 3 (2014), 676-682$$pSpan. j. agric. res.$$tSPANISH JOURNAL OF AGRICULTURAL RESEARCH$$x1695-971X
000062039 8564_ $$s267910$$uhttp://zaguan.unizar.es/record/62039/files/texto_completo.pdf$$yVersión publicada
000062039 8564_ $$s106569$$uhttp://zaguan.unizar.es/record/62039/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000062039 909CO $$ooai:zaguan.unizar.es:62039$$particulos$$pdriver
000062039 951__ $$a2017-12-11-14:02:27
000062039 980__ $$aARTICLE