Universidad de Zaragoza Repository

Resumen: Blood vessels are highly organized and complex structure, which are far more than simple tubes conducting the blood to almost any tissue of the body. The fine structure of the wall of blood vessels has been studied previously using the electron microscope, but the presence the telocytes associated with vasculature, a specific new cellular entity, has not been studied in depth. Interestingly, telocytes have been recently found in the epicardium, myocardium, endocardium, human term placenta, duodenal lamina propria and pleura. We show the presence of telocytes located on the extracellular matrix of blood vessels (arterioles, venules and capillaries) by immunohistochemistry and transmission electron microscopy. Also, we demonstrated the first evidence of a primary cilium in telocytes. Several functions have been proposed for these cells. Here, the telocyte-blood vessels cell proximity, the relationship between telocytes, exosomes and nervous trunks may have a special significance.
Idioma: Inglés
DOI: 10.1111/j.1582-4934.2011.01312.x
Año: 2011
Publicado en: Journal of Cellular and Molecular Medicine 15, 12 (2011), 2594-2600
ISSN: 1582-1838
Factor impacto JCR: 4.125 (2011)
Categ. JCR: MEDICINE, RESEARCH & EXPERIMENTAL rank: 22 / 112 = 0.196 (2011) - Q1 - T1
Categ. JCR: CELL BIOLOGY rank: 65 / 181 = 0.359 (2011) - Q2 - T2
Financiación: info:eu-repo/grantAgreement/ES/DGA/B83
Financiación: info:eu-repo/grantAgreement/ES/IACS/PIPAMER-10-001
Tipo y forma: Article (Published version)
Área (Departamento): Area Histología (Dpto. Anatom.Histolog.Humanas)
Área (Departamento): Area Anatom.Embriol.Humana (Dpto. Anatom.Histolog.Humanas)

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